PRINCIPAL SCIENTIST/ASSOCIATE DIRECTOR, BIOCHEMISTRY
About Ikena
Ikena Oncology is a clinical-stage biotechnology company that
discovers and develops patient-directed, biomarker-driven therapies
for cancer patients who need life-saving treatment, by understanding
what drives their disease. Ikena is advancing five clinical,
preclinical, and discovery programs. Ikena has entered into a global
strategic collaboration with Bristol Myers Squibb and raised capital
from top tier investors OrbiMed Advisors and Atlas Venture.
Role Description
Ikena Oncology is seeking a highly talented, diversely experienced,
and motivated Biochemistry lead to join our Discovery Biology team. As
the first dedicated biochemist, this individual will leverage their
expertise to help drive the Ikena drug discovery engine and support
our novel targeted small molecule programs.
RESPONSIBILITIES
OVERSEE AND CONDUCT BIOCHEMICAL EFFORTS IN-HOUSE AND AT CRO DEVELOP
MEDIUM-TO-HIGH THROUGHPUT PLATE-BASED BIOCHEMICAL ASSAYS TO FACILITATE
COMPOUND SCREENING, CHARACTERIZE COMPOUNDS, ELUCIDATE MECHANISM OF
ACTION, AND SUPPORT MEDICINAL CHEMISTRY EFFORTS PROVIDE
BIOCHEMISTRY/STRUCTURAL BIOLOGY EXPERTISE TO SUPPORT IKENAS SMALL
MOLECULE DISCOVERY PROGRAMS INCLUDING TARGETED PROTEIN DEGRADATION
DESIGN EXPRESSION CONSTRUCTS FOR HIGH QUALITY PROTEIN PRODUCTION
CHARACTERIZE PURIFIED PROTEINS USING A RANGE OF BIOCHEMICAL AND
BIOPHYSICAL TECHNIQUES ENZYME AND/OR BINDING KINETIC ANALYSIS WORK
CLOSELY WITH CROS TO ENABLE BIOCHEMISTRY EFFORTS, INCLUDING, PROTEIN
EXPRESSION AND PURIFICATION, ASSAY DEVELOPMENT, HIGH-THROUGHPUT
SCREENING, MECHANISTIC STUDIES, AND STRUCTURAL BIOLOGY LEAD
EXPERIMENTAL DESIGN AND ASSAY DEVELOPMENT AND THE INTERPRETATION OF
RESULTS INDEPENDENTLY COMMUNICATE RESULTS TO CROSS-FUNCTIONAL PROJECT
TEAMS AND UPDATE SENIOR MANAGEMENT ON OVERALL PROJECT STRATEGY AND
GOALS SUPPORT THE ORGANIZATION BY MAINTAINING A WORK ENVIRONMENT
FOCUSED ON SCIENTIFIC INTEGRITY AND FOSTERS LEARNING, OPEN
COMMUNICATION, AND COLLABORATION
Qualifications
PH.D. WITH **APPLY ON THE WEBSITE** YEARS OF HANDS-ON EXPERIENCE, OR
MS WITH **APPLY ON THE WEBSITE** YEARS OF HANDS-ON EXPERIENCE IN
BIOCHEMISTRY. INDUSTRY LABORATORY EXPERIENCE PREFERRED STRONG
LABORATORY EXPERTISE PERTAINING TO BIOCHEMISTRY AND RELATED
BIOPHYSICAL SCIENCES UNDERSTANDING AND DEMONSTRATED PERFORMANCE IN
TARGETED PROTEIN DEGRADATION KNOWLEDGE OF COMPUTER SOFTWARE AND
MICROSOFT APPLICATIONS (WORD, EXCEL, POWERPOINT, GRAPHPAD AND PRISM)
DETAIL-ORIENTED, WITH EXCELLENT ORGANIZATION AND RECORD-KEEPING SKILLS
CAPABLE OF WORKING BOTH INDEPENDENTLY AND IN A COLLABORATIVE
ENVIRONMENT ABILITY TO COMMUNICATE RESULTS IN WRITTEN AND VERBAL FORM
PERSONAL ATTRIBUTES: TEAM ORIENTED, GOAL-DRIVEN, ORGANIZED, HIGHLY
COLLABORATIVE, OPEN-MINDED, DATA-DRIVEN, CREATIVE, PERSISTENT IN THE
FACE OF OBSTACLES AND UNCERTAINTY, FLEXIBLE, SELF-AWARE OF STRENGTHS
AND WEAKNESSES, OBJECTIVE IN THE EVALUATION OF DATA AND STRONGLY
OPTIMISTIC ABOUT OVERCOMING OBSTACLES.
andlt; BACK
PRINCIPAL SCIENTIST/ASSOCIATE DIRECTOR, BIOCHEMISTRY
About Ikena
Ikena Oncology is a clinical-stage biotechnology company that
discovers and develops patient-directed, biomarker-driven therapies
for cancer patients who need life-saving treatment, by understanding
what drives their disease. Ikena is advancing five clinical,
preclinical, and discovery programs. Ikena has entered into a global
strategic collaboration with Bristol Myers Squibb and raised capital
from top tier investors OrbiMed Advisors and Atlas Venture.
Role Description
Ikena Oncology is seeking a highly talented, diversely experienced,
and motivated Biochemistry lead to join our Discovery Biology team. As
the first dedicated biochemist, this individual will leverage their
expertise to help drive the Ikena drug discovery engine and support
our novel targeted small molecule programs.
RESPONSIBILITIES
OVERSEE AND CONDUCT BIOCHEMICAL EFFORTS IN-HOUSE AND AT CRO DEVELOP
MEDIUM-TO-HIGH THROUGHPUT PLATE-BASED BIOCHEMICAL ASSAYS TO FACILITATE
COMPOUND SCREENING, CHARACTERIZE COMPOUNDS, ELUCIDATE MECHANISM OF
ACTION, AND SUPPORT MEDICINAL CHEMISTRY EFFORTS PROVIDE
BIOCHEMISTRY/STRUCTURAL BIOLOGY EXPERTISE TO SUPPORT IKENAS SMALL
MOLECULE DISCOVERY PROGRAMS INCLUDING TARGETED PROTEIN DEGRADATION
DESIGN EXPRESSION CONSTRUCTS FOR HIGH QUALITY PROTEIN PRODUCTION
CHARACTERIZE PURIFIED PROTEINS USING A RANGE OF BIOCHEMICAL AND
BIOPHYSICAL TECHNIQUES ENZYME AND/OR BINDING KINETIC ANALYSIS WORK
CLOSELY WITH CROS TO ENABLE BIOCHEMISTRY EFFORTS, INCLUDING, PROTEIN
EXPRESSION AND PURIFICATION, ASSAY DEVELOPMENT, HIGH-THROUGHPUT
SCREENING, MECHANISTIC STUDIES, AND STRUCTURAL BIOLOGY LEAD
EXPERIMENTAL DESIGN AND ASSAY DEVELOPMENT AND THE INTERPRETATION OF
RESULTS INDEPENDENTLY COMMUNICATE RESULTS TO CROSS-FUNCTIONAL PROJECT
TEAMS AND UPDATE SENIOR MANAGEMENT ON OVERALL PROJECT STRATEGY AND
GOALS SUPPORT THE ORGANIZATION BY MAINTAINING A WORK ENVIRONMENT
FOCUSED ON SCIENTIFIC INTEGRITY AND FOSTERS LEARNING, OPEN
COMMUNICATION, AND COLLABORATION
Qualifications
PH.D. WITH **APPLY ON THE WEBSITE** YEARS OF HANDS-ON EXPERIENCE, OR
MS WITH **APPLY ON THE WEBSITE** YEARS OF HANDS-ON EXPERIENCE IN
BIOCHEMISTRY. INDUSTRY LABORATORY EXPERIENCE PREFERRED STRONG
LABORATORY EXPERTISE PERTAINING TO BIOCHEMISTRY AND RELATED
BIOPHYSICAL SCIENCES UNDERSTANDING AND DEMONSTRATED PERFORMANCE IN
TARGETED PROTEIN DEGRADATION KNOWLEDGE OF COMPUTER SOFTWARE AND
MICROSOFT APPLICATIONS (WORD, EXCEL, POWERPOINT, GRAPHPAD AND PRISM)
DETAIL-ORIENTED, WITH EXCELLENT ORGANIZATION AND RECORD-KEEPING SKILLS
CAPABLE OF WORKING BOTH INDEPENDENTLY AND IN A COLLABORATIVE
ENVIRONMENT ABILITY TO COMMUNICATE RESULTS IN WRITTEN AND VERBAL FORM
PERSONAL ATTRIBUTES: TEAM ORIENTED, GOAL-DRIVEN, ORGANIZED, HIGHLY
COLLABORATIVE, OPEN-MINDED, DATA-DRIVEN, CREATIVE, PERSISTENT IN THE
FACE OF OBSTACLES AND UNCERTAINTY, FLEXIBLE, SELF-AWARE OF STRENGTHS
AND WEAKNESSES, OBJECTIVE IN THE EVALUATION OF DATA AND STRONGLY
OPTIMISTIC ABOUT OVERCOMING OBSTACLES.
We need : English (Good)
Type: Permanent
Payment:
Category: Others
